Studies on Distribution of Cerebral Blood Flow with Thorium B-Labeled Erythrocytes

In recent years there have been a number of attempts to study the cerebral blood flow. Kety and Schmidt' between 1945 and 1948 introduced a nitrous oxide method, and for the firet time measured quantitatively the minute volume of the brain. This was the first occasion on which the total oxygen consumption of the brain was measured through simultaneous determination of the arterial venous oxygen difference of the brain. In Germany, this method was first introduced between 1951 and 1952 in the clinic in Diisseldorf by Bodechtel* and the method was modified and improved by Bernsmeier and Siemons.